Progress in Multiple Sclerosis Research
Nova Publishers, 2005 - Broj stranica: 209
Multiple sclerosis (MS) is a life-long chronic disease diagnosed primarily in young adults. During an MS attack, inflammation occurs in areas of the white matter of the central nervous system (nerve fibres that are the site of MS lesions) in random patches called plaques. This process is followed by destruction of myelin, which insulates nerve cell fibres in the brain and spinal cord. Myelin facilitates the smooth, high-speed transmission of electrochemical messages between the brain, the spinal cord, and the rest of the body. The initial symptom of MS is often blurred or double vision, red-green colour distortion, or even blindness in one eye. Most MS patients experience muscle weakness in their extremities and difficulty with co-ordination and balance. Most people with MS also exhibit paresthesias, transitory abnormal sensory feeling such as numbness or "pins and needles." Some may experience pain or loss of feeling. About half of people with MS experience cognitive impairments such as difficulties with concentration, attention, memory, and judgement. This volume presents leading research from around the globe.
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Acta Neurol Scand Ann Neurol antibodies antigen assessment associated axonal Azathioprine brain cells cerebral cerebrospinal fluid chronic illness Clin clinical cognitive controls countries Croatia cytokines decreased demyelinating disease depression diagnosis differences disability disorders Epidemiology Epidemiology of multiple experience factors fMRI genetic Glatiramer acetate Gorski Kotar human IFN-B IFN-ſ immune incidence increased individuals infection inflammatory Interferon beta-1b interferon-beta interleukin-12 Ishihara scores Kočevje Koch Kralik lesions living lymphocytes magnetic resonance imaging Materljan mechanisms mortality rates mRNA multiple sclerosis multiple sclerosis patients myelin Neurol Neurosurg Neurology onset optic neuropathy participants patients with multiple patients with relapsing-remitting population prevalence rates primary progressive progressive multiple sclerosis psychiatric regions relapse relapsing-remitting multiple sclerosis relationship reported response Rijeka secondary progressive multiple self-efficacy Sepčić serum sexuality side effects significant social suggest symptoms treatment urinary incontinence viral virus viruses visual acuities white matter women Zagreb