Current Medicinal Chemistry |
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5-HT,D affinity 5-HT1D receptor acid acridine action activity agents agonists alkyl alniditan amide amino amsacrine analogs antimigraine antitumor assay AT-rich avitriptan Bentham Science Publishers benzylpenicillin bind to DNA binders bithiazole bleomycin brain homogenate camptothecin carbamate carboxylate CDSs cells CGRP Chemical Delivery Systems chromophore Cl-ENU clinical complex compounds coniuqates covalent crosslinking cytotoxic derivatives dihydropyridine distamycin DNA binding DNA cleavage drug eletriptan ellipticine enediyne enzymatic ester groove of DNA hybrid hydration hydrolysis imidazole increased indole inhibit interaction intercalation lexitropsin conjugates ligand linkage linker lipophilicity Medicinal Chemistry migraine minor groove minor groove binding moiety molecular molecules naratriptan netropsin nitrogen oxadiazole oxidation pharmacological phenytoin potent properties psoralen pyrrole quaternary salt redox ring rizatriptan selectivity sequence side chain spacer specific stability strand structural studies substituent subtypes sumatriptan synthesized targetor topoisomerase topoisomerase II tryptamine vitro vivo zolmitriptan