Current Medicinal Chemistry |
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5-lipoxygenase AAlPA lC50 amino acid analogs antagonist activity antibacterial aorta aortic aspartic acid proteases asperlicin assay B-ET Bentham Science Publishers benzodiazepine binding affinity bond bovine C-terminal carboxylic acid CCK-B Antagonists CCK-B receptor chiral CO2H COOH derivatives Devazepide DNA gyrase effect enantiomers endothelial cells endothelin enzyme ET-1 induced ETA receptor FLAP function guinea pig human hydroperoxide hydrophobic hypertensive indomethacin induced by ET-1 inhibition interactions isolated Leu-Trp ligands lnterestingly mediated membrane fractions metabolic metalloprotease mg/kg molecular non-peptide NSAlDs ofloxacin oxygen peptide PGH synthase PGH synthase-2 phosphoramidon plasma porcine potent and selective pressor response propionic acids protease protein pulmonary artery quinolones rabbit radical receptor subtypes renal reported residues rosoxacin series of compounds similar smooth muscle smooth muscle cells specific SRTX-6c structure studies substitution Table tissues topo ll inhibitors type B hydroxamates vasoconstriction vitro vivo