Alzheimer DiseaseRobert D. Terry Lippincott Williams & Wilkins, 1999 - Broj stranica: 457 The Second Edition of this highly acclaimed volume examines every major aspect of Alzheimer disease -- clinical, epidemiologic, structural, chemical, genetic, molecular, and therapeutic. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The broad coverage of AD in this book benefits clinicians, educators, investigators, and health administrators. |
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Stranica 259
Robert D. Terry. B amyloid protein precursor of Alzheimer's disease are labeled by antisera to the ẞ amyloid protein . Biochem Biophys Res Commun 1989 ; 165 : 182-188 . 70. Oltersdorf T , Fritz LC , Schenk DB , et al . The secreted form ...
Robert D. Terry. B amyloid protein precursor of Alzheimer's disease are labeled by antisera to the ẞ amyloid protein . Biochem Biophys Res Commun 1989 ; 165 : 182-188 . 70. Oltersdorf T , Fritz LC , Schenk DB , et al . The secreted form ...
Stranica 307
... precursor protein stimulates neurite outgrowth of hippocam- pal neurons in an isoform - dependent manner . J Neurosci 1995 ; 15 : 2157-2167 . 24. Schubert D , Jin L ... AMYLOID PRECURSOR PROTEIN AND THE MECHANISM OF ALZHEIMER DISEASE / 307.
... precursor protein stimulates neurite outgrowth of hippocam- pal neurons in an isoform - dependent manner . J Neurosci 1995 ; 15 : 2157-2167 . 24. Schubert D , Jin L ... AMYLOID PRECURSOR PROTEIN AND THE MECHANISM OF ALZHEIMER DISEASE / 307.
Stranica 322
... amyloid protein precursor to potentially amyloidogenic deriva- tives . Science 1992 ; 255 : 728-730 . 22. Haass C , Koo EH , Mellon A , Hung AY , Selkoe DJ . Targetting of cell surface B - amyloid precursor protein to lysosomes ...
... amyloid protein precursor to potentially amyloidogenic deriva- tives . Science 1992 ; 255 : 728-730 . 22. Haass C , Koo EH , Mellon A , Hung AY , Selkoe DJ . Targetting of cell surface B - amyloid precursor protein to lysosomes ...
Sadržaj
Clinical Presentation | 6 |
Noncognitive Symptoms of Alzheimer Disease | 25 |
Neuropsychology of Alzheimer Disease | 39 |
Autorska prava | |
Broj ostalih dijelova koji nisu prikazani: 26
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Uobičajeni izrazi i fraze
abnormal Acad Sci USA activity allele Alzheimer disease Alzheimer's disease amyloid precursor protein Ann Neurol ApoE apolipoprotein apoptosis Arch Neurol areas Aẞ associated atrophy B-amyloid basal forebrain behavioral Biol Brain Res cells cerebral cortex cholinergic cholinergic neurons chromosome clinical cognitive impairment correlation cortical deficits degeneration demented density diagnosis disorders drug effects elderly entorhinal ethnic Exp Neurol familial frontal frontotemporal dementia function gene genetic growth factor hippocampus human immunoreactivity increased lesions levels Lewy body lobe Masliah memory mer's disease metabolism microglia monkeys mutations Natl Acad Sci neocortex neuritic Neurobiol Aging neurodegenerative neurofibrillary tangles neurofilament Neurology neuronal loss neurons neuropsychological Neurosci Neurosci Lett normal onset Parkinson disease pathological patients peptide phosphorylation presenilin prevalence Proc Natl Acad Prpsc Psychiatry receptor regions reported risk factors senile dementia senile plaques studies subcortical symptoms synaptic syndrome tau protein temporal tion transgenic mice trophic factors vascular dementia