Current Medicinal Chemistry |
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acetate acid units acylation addition afforded agents alkyl amide amine amino group analogs asymmetric synthesis B-alanine B-amino acids B-amino esters B-lactam B-peptides Bentham Science Publishers benzyl binding biological activity breast cancer cell lines carboxylic catalytic hydrogenation Chem chiral compounds conformation COOH corresponding coworkers COZH Current Medicinal Chemistry cyclic cytotoxicity deprotection derivatives diastereomeric diastereoselectivity docetaxel drug enamine enantiopure enantioselective enantioselective synthesis enolate enzymatic ethyl fold H-bonding helical structure helix hybrid constructs hydrolysis imine inhibitors integrin investigated isomer ligand Medicinal Chemistry methanol modification moiety novel NSCL octreotide oligomers overall yield paclitaxel paclitaxel and docetaxel Pd/C peptide Pharmaceutical pharmacophore phenyl platelet platelet aggregation inhibition potent prepared prodrug proteins racemic reaction reagent recently receptor reported resolution resulting ring salt second generation taxoids secondary structures side chains stereoselective substituted synthesis of B-amino t-BuO Table taxoids vivo