Current Medicinal Chemistry

6-selective AcHN amine analogues containing antagonists antigen aromatic Asp4 Asp7 asparagine backbone Bentham Science Publishers benzyl binding affinity bioactive building blocks C-terminal carbohydrate carbohydrate moiety carbohydrate specific carboxylic cell receptor cell response cleavage complex compounds conformation constrained COZH cyclic deltorphin deprotection dermenkephalin dimer DPDPE effect elicit enzymatic epitope Fmoc galabiose GIy4Id glycopeptide synthesis glycopeptides glycoproteins glycosides glycosylated amino acids glycosylation of Fmoc helix helper T cells high affinity hybridomas hydrogen bonding hydrophobic hydroxyl groups immune response immunogenic ligand linkage MHC II MHC molecules modifications NHFmoc NOEs nonselective obtained oligosaccharides opioid binding opioid receptor orders of magnitude peptide pharmacophoric pNPY position protective groups proteins proton receptor affinity receptor binding receptor type reduced replacement residue four residue three resulted role rotamer saccharides sequence serine and threonine side chain solid-phase synthesis structure studies substituted tetrapeptide threonine TMSO tripeptide Tyr1